1-Lithio-1,3-dienes: Useful Building Blocks for Cyclic Compounds

1-(Triethoxysilyl)buta-1,3-dienes—New Building Blocks for Stereoselective Synthesis of Unsymmetrical (E,E)-1,4-Disubstituted 1,3-dienes

A convenient methodology for the highly stereoselective synthesis of unsymmetrical (1E,3E)-1,4-disubstituted 1,3-dienes based on palladium-catalyzed Hiyama cross-coupling reaction of 1-(triethoxysilyl)-substituted buta-1,3-dienes with aryl iodides is reported.

Building Blocks for Nanotransporters

Chemoenzymic Synthesis of Chiral Furan Derivatives: Useful Building Blocks for Optically Active Structures

60%; [a]25D -13.4O (c 0.7, MeOH);24 'H NMR (CDCld 8 0.95 (3 H, d, J = 6.0 Hz), 1.40-2.00 (3 H, m), 2.15 (2 H, br s), 3.30-3.90 (4 H, m). Synthesis of 10. This compound was synthesized by starting from cis-3Dc as reported above for cis-3Ac. The diastereomeric ratio has been obtained by capillary GC analysis (150 OC 0 min/4 OC/min/250 OC 5 min, tR = 13.72 (major), 14.10 (minor)). The yield is rep...

Early metal di- and tricyanometalates: Useful building blocks for constructing magnetic clusters.

Treatment of mer-VCl3(THF)3 with KTp [Tp = hydridotris(3,5-dimethylpyrazol-1-yl)borate], followed by [NEt4]CN in acetonitrile, affords [NEt4][(Tp)V(III)(CN)3].H2O (1.H2O); aerobic oxidation affords [NEt4][(Tp)V(IV)(O)(CN)2] (2). Subsequent treatment of 2 with Mn(II)(OTf)2 (OTf = trifluoromethanesulfonate) and 2,2'-bipyridine affords {[(Tp)V(O)(CN)2]2[Mn(II)(bipy)2]2[OTf]2}.2MeCN (3). Magnetic m...

Formylnitroenamines: useful building blocks for nitrated pyridones and aminopyridines with functional groups.

beta-formyl-beta-nitroenamines possess both an electrophilic formyl group and a nucleophilic amino group and, therefore, serve as C3N1 building blocks having a nitro group to afford nitropyridones and aminonitropyridines with a functional group at the 3-position. Upon treatment with malonic acid derivatives or beta-keto esters, nitropyridones were obtained, whereas reactions with functionalized...